Hold the Door: Role of the Gut Barrier in Diabetes

被引：24

作者：

Martin, Anthony ^{[1
]}

Devkota, Suzanne ^{[1
,2
]}

机构：

[1] Cedars Sinai Med Ctr, Inflammatory Bowel & Immunobiol Res Inst, Los Angeles, CA 90048 USA

[2] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90095 USA

来源：

CELL METABOLISM | 2018年 / 27卷 / 05期

关键词：

INSULIN-RESISTANCE; OBESITY;

D O I：

10.1016/j.cmet.2018.04.017

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

While metabolic tissues such as adipose, liver, muscle, and pancreas have been extensively studied in dys-metabolism, the contribution of the gut remains poorly understood. In a recent Science article, Thaiss et al. (2018) unravel mechanisms underlying intestinal permeability observed in obesity and link barrier dysfunction and risk for infection with hyperglycemia.

引用

页码：949 / 951

页数：4

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