Ligand exchange chiral separations by cyclodextrin derivatives in capillary electrophoresis

被引：35

作者：

Cucinotta, V

Giuffrida, A

Grasso, G

Maccarrone, G

Vecchio, G

机构：

[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

[2] CNR, Ist Biostrutture & Bioimmagini, Sez Catania, I-95125 Catania, Italy

来源：

ANALYST | 2003年 / 128卷 / 02期

关键词：

D O I：

10.1039/b210003g

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A beta-cyclodextrin substituted by an imidazole-bound histamine (CDmh) was successfully used to separate underivatised tryptophan racemate in capillary electrophoresis in the presence of copper( II) ion by the ligand exchange mechanism. To the best of our knowledge, this is the first example of a cyclodextrin derivative behaving as the first coordination sphere ligand in the complex added to the background electrolyte (BGE).

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页码：134 / 136

页数：3

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