Apoptosis: Implications for inflammatory bowel disease

被引：33

作者：

Levine, AD

机构：

[1] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Dept Pharmacol, Cleveland, OH 44106 USA

[3] Case Western Reserve Univ, Ireland Canc Ctr, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA

来源：

INFLAMMATORY BOWEL DISEASES | 2000年 / 6卷 / 03期

关键词：

apoptosis; review; intestinal epithelial cells; lamina propria lymphocytes; mucosa;

D O I：

10.1097/00054725-200008000-00006

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Cells of the intestinal mucosa live in a harsh environment and therefore rely heavily on the highly regulated process of cell death, apoptosis, to maintain tissue integrity, Imbalance in the intracellular events that modulate apoptosis may contribute to the pathogenesis of inflammatory bowel disease.

引用

收藏

页码：191 / 205

页数：15

相关论文

共 197 条

[21] Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis [J].

Boirivant, M ;

Marini, M ;

Di Felice, G ;

Pronio, AM ;

Montesani, C ;

Tersigni, R ;

Strober, W .

GASTROENTEROLOGY, 1999, 116 (03) :557-565

[22] BCL-2 ONCOPROTEIN IN COLORECTAL HYPERPLASTIC POLYPS, ADENOMAS, AND ADENOCARCINOMAS [J].

BOSARI, S ;

MONEGHINI, L ;

GRAZIANI, D ;

LEE, AKC ;

MURRAY, JJ ;

COGGI, G ;

VIALE, G .

HUMAN PATHOLOGY, 1995, 26 (05) :534-540

[23] Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization [J].

Bossy-Wetzel, E ;

Newmeyer, DD ;

Green, DR .

EMBO JOURNAL, 1998, 17 (01) :37-49

[24] GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR CONTRIBUTES TO ENHANCED MONOCYTE SURVIVAL IN CHRONIC ATOPIC-DERMATITIS [J].

BRATTON, DL ;

HAMID, Q ;

BOGUNIEWICZ, M ;

DOHERTY, DE ;

KAILEY, JM ;

LEUNG, DYM .

JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (01) :211-218

[25] Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease [J].

Braun, MY ;

Lowin, B ;

French, L ;

AchaOrbea, H ;

Tschopp, J .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (02) :657-661

[26]

Bregenholt S, 1998, EUR J IMMUNOL, V28, P3655, DOI 10.1002/(SICI)1521-4141(199811)28:11<3655::AID-IMMU3655>3.0.CO

[27]

2-9

[28] OXIDATIVE STRESS AS A MEDIATOR OF APOPTOSIS [J].

BUTTKE, TM ;

SANDSTROM, PA .

IMMUNOLOGY TODAY, 1994, 15 (01) :7-10

[29]

Ciccocioppo R, 1999, ITAL J GASTROENTEROL, V31, P162

[30]

Clarke PGH, 1996, ANAT EMBRYOL, V193, P81

← 1 2 3 4 5 6 7 8 9 10 →