Preparation of nanocrystalline zinc-substituted hydroxyapatite films and their biological properties

被引：31

作者：

Galindo, Tania Guadalupe Penaflor ^{[1
]}

Kataoka, Takuya ^{[1
]}

Fujii, Shuji ^{[1
]}

Okuda, Mitushiro ^{[2
,3
]}

Tagaya, Motohiro ^{[1
,4
]}

机构：

[1] Nagaoka Univ Technol, Dept Mat Sci & Technol, 1603-1 Kamitomioka, Nagaoka, Niigata 9402188, Japan

[2] CIC NanoGUNE, Tolosa Hiribidea 76, E-20018 Donostia San Sebastian, Basque Country, Spain

[3] Basque Fdn Sci, Ikerbasque, Alameda Urquijo 36-5,Plaza Bizkaia, E-48011 Bilbao, Basque Country, Spain

[4] Nagaoka Univ Technol, Top Runner Incubat Ctr Acad Ind Fus, 1603-1 Kamitomioka, Nagaoka, Niigata 9402188, Japan

来源：

COLLOID AND INTERFACE SCIENCE COMMUNICATIONS | 2016年 / 10-11卷

基金：

日本学术振兴会;

关键词：

Nano-bio interfaces; Hydroxyapatite; Electrophoretic deposition; Biomaterials; Bioceramics; ELECTROPHORETIC DEPOSITION; COATINGS; TITANIUM; ADHESION; COPPER;

D O I：

10.1016/j.colcom.2016.03.005

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

Nanocrystalline zinc (Zn)-substituted hydroxyapatite (HAp) films were prepared and electrically-plated on a titanium-coated silicone to investigate the biological properties. The hydroxyapatite nanocrystals with the different initial molar (Zn+Ca)/P ratios (1.67 and 2.00) and Zn ion concentrations were synthesized and subsequently coated by an electrophoretic deposition method to successfully form homogenous thin films. The nanocrystalline films provided bioactive properties based on the fibroblast ingrowth as well as the reduction in the number of viable Escherichia coli. Therefore, the optimized cytocompatible and antibacterial properties of the films by the effective Zn ion substituted in the HAp will be useful as a silicone surface modification technique. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：15 / 19

页数：5

共 23 条

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