Systems biology - An engineering perspective

被引:48
作者
Kremling, A. [1 ]
Saez-Rodriguez, J. [1 ]
机构
[1] Max Planck Inst Dynam Complex Tech Syst, Syst Biol Grp, D-39106 Magdeburg, Germany
关键词
modeling framework; model reduction; model verification; control engineering;
D O I
10.1016/j.jbiotec.2007.02.009
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The interdisciplinary field of systems biology has evolved rapidly over the last years. Different disciplines have aided the development of both its experimental and theoretical branches. One field, which has played a significant role is engineering science and, in particular chemical engineering. Here, we review and illustrate some of these contributions, ranging from modeling approaches to model analysis with a special focus on technique which have not yet been substantially exploited but can be potentially useful in the analysis of biochemical systems. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:329 / 351
页数:23
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