Nicotine effects on skin: Are they positive or negative?

被引：68

作者：

Misery, L ^{[1
]}

机构：

[1] Univ Hosp, Dept Dermatol, Lab Cutaneous Neurobiol, F-29609 Brest, France

来源：

EXPERIMENTAL DERMATOLOGY | 2004年 / 13卷 / 11期

关键词：

fibroblast; inflammation; keratinocytes; nicotine; skin;

D O I：

10.1111/j.0906-6705.2004.00274.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The adverse effects of tobacco on the skin are well known but the role of nicotine is more controversial. Nicotinic receptors are expressed in the skin, on keratinocytes, fibroblasts and blood vessels. Nicotine induces vasoconstriction associated with local hyperaemia. It inhibits inflammation through effects on central and peripheral nervous system and through direct effect on immune cells. It delays wound healing and accelerates skin aging. The role of nicotine on skin diseases remains unclear. Therapeutic effects of nicotine could be possible and this a new stimulating field of research.

引用

页码：665 / 670

页数：6

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