The ATPase subunit 6 gene of Leptomonas seymouri (Trypanosomatidae) is transcribed and edited as a polycistronic mRNA

被引：4

作者：

Bessolitsina, EA ^{[1
]}

Fedyakov, AV ^{[1
]}

Merzlyak, EM ^{[1
]}

Kolesnikov, AA ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Moscow 119992, Russia

来源：

MOLECULAR BIOLOGY | 2005年 / 39卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

RNA editing; trypanosomatidae; kinetoplast; polycistronic RNA; pre-mRNA maturation;

D O I：

10.1007/s11008-005-0007-y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The maturation of mRNA was studied for the Leptomonas seymouri mitochondrial A6 gene coding for ATPase subunit 6. RT-PCR showed that the cytochrome b and A6 genes are transcribed to produce a polycistronic RNA. The RT-PCR products, containing the cDNAs of these genes, were cloned and sequenced. Comparison of the sequence for 12 clones revealed four types of transcripts representing partly or completely edited products of A6. Two different variants of completely edited A6 mRNAs were found.

引用

页码：53 / 57

页数：5

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