Rapid microwave-enhanced, solventless Sonogashira coupling reaction on alumina

被引：142

作者：

Kabalka, GW ^{[1
]}

Wang, L

Namboodiri, V

Pagni, RM

机构：

[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA

[2] Univ Tennessee, Dept Radiol, Knoxville, TN 37996 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 27期

关键词：

coupling reactions; palladium; microwave heating; alkynes;

D O I：

10.1016/S0040-4039(00)00774-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A microwave-enhanced, solventless Sonogashira coupling reaction has been developed. Terminal alkynes couple with aryl or alkenyl iodide on palladium-doped alumina in the presence of triphenylphosphine and cuprous iodide to provide high yields of products. (C) 2000 Published by Elsevier Science Ltd.

引用

页码：5151 / 5154

页数：4