Synthesis of functionalized acetophenones by [3+3] cyclizations of 1,3-bis-silyl enol ethers with 2-acetyl-3-silyloxyalk-2-en-1-ones

被引：21

作者：

Dede, R ^{[1
]}

Langer, P ^{[1
]}

机构：

[1] Univ Greifswald, Inst Chem & Biochem Ernst Moritz Arndt, D-17487 Greifswald, Germany

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 50期

关键词：

acetophenones; cyclizations; regioselectivity; silyl enol ethers;

D O I：

10.1016/j.tetlet.2004.10.104

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The TiCl4 mediated cyclization of 1,3-bis-silyl enol ethers with 2-acetyl-1-silyloxybut-1-en-3-one and 3-acetyl-4-silyloxypcnt-3-en-2-one, readily prepared from 3-formyl(acetylacetone) and triacetyl methane, afforded a variety of functionalized acetophenones. (C) 2004 Published by Elsevier Ltd.

引用

页码：9177 / 9179

页数：3

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