Specific derivatization of lysozyme in aqueous solution with Re(CO)3(H2O)3+

被引：34

作者：

Binkley, Sarah L. ^{[1
]}

Ziegler, Christopher J. ^{[1
]}

Herrick, Richard S. ^{[2
]}

Rowlett, Roger S. ^{[3
]}

机构：

[1] Univ Akron, Dept Chem, Akron, OH 44325 USA

[2] Coll Holy Cross, Dept Chem, Worcester, MA 01610 USA

[3] Colgate Univ, Dept Chem, Hamilton, NY 13346 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 08期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

SOLID-PHASE SYNTHESIS; STRUCTURAL-CHARACTERIZATION; IMAGING AGENTS; DNA-BINDING; COMPLEXES; RADIOPHARMACEUTICALS; STRATEGY; LIGANDS; GUANINE;

D O I：

10.1039/b923688k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of Re(CO)(3)(H2O)(3)(+) with hen egg lysozyme in aqueous solution results in a single covalent adduct; single crystal X-ray diffraction shows that the rhenium tricarbonyl cation binds to His15 in two significantly populated rotamer conformations.

引用

收藏

页码：1203 / 1205

页数：3

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