Structural biology - ESCRT service

被引:3
作者
Alam, Steven L. [1 ]
Sundquist, Wesley I. [1 ]
机构
[1] Univ Utah, Dept Biochem, Salt Lake City, UT 84112 USA
关键词
D O I
10.1038/447921a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The sorting and degradation of cell-surface proteins are essential for cellular homeostasis. The ESCRT-I complex is known to be involved in these events, and new structural findings elucidate its core architecture.
引用
收藏
页码:921 / 922
页数:2
相关论文
共 12 条
[1]   New component of ESCRT-I regulates endosomal sorting complex assembly [J].
Chu, Tony ;
Sun, Ji ;
Saksena, Suraj ;
Emr, Scott D. .
JOURNAL OF CELL BIOLOGY, 2006, 175 (05) :815-823
[2]   Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12 [J].
Curtiss, Matt ;
Jones, Charles ;
Babst, Markus .
MOLECULAR BIOLOGY OF THE CELL, 2007, 18 (02) :636-645
[3]   Structural insight into the ESCRT-I/-II link and its role in MVB trafficking [J].
Gill, David J. ;
Teo, Hsiangling ;
Sun, Ji ;
Perisic, Olga ;
Veprintsev, Dmitry B. ;
Emr, Scott D. ;
Williams, Roger L. .
EMBO JOURNAL, 2007, 26 (02) :600-612
[4]   The ESCRT complexes: Structure and mechanism of a membrane-trafficking network [J].
Hurley, James H. ;
Emr, Scott D. .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2006, 35 :277-298
[5]   Three ways to make a vesicle [J].
Kirchhausen, T .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2000, 1 (03) :187-198
[6]   Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer [J].
Kostelansky, Michael S. ;
Schluter, Cayetana ;
Tam, Yuen Yi C. ;
Lee, Sangho ;
Ghirlando, Rodolfo ;
Beach, Bridgette ;
Conibear, Elizabeth ;
Hurley, James H. .
CELL, 2007, 129 (03) :485-498
[7]   Structural and functional organization of the ESCRT-I trafficking complex [J].
Kostelansky, MS ;
Sun, J ;
Lee, SH ;
Kim, J ;
Ghirlando, R ;
Hierro, A ;
Emr, SD ;
Hurley, JH .
CELL, 2006, 125 (01) :113-126
[8]   Retrovirus budding [J].
Morita, E ;
Sundquist, WI .
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2004, 20 :395-425
[9]  
MORITA E, IN PRESS CELL HOST M
[10]   Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway [J].
Oestreich, Andrea J. ;
Davies, Brian A. ;
Payne, Johanna A. ;
Katzmann, David J. .
MOLECULAR BIOLOGY OF THE CELL, 2007, 18 (02) :646-657