Identification of a human population infected with simian foamy viruses

被引：176

作者：

Heneine, W ^{[1
]}

Switzer, WM

Sandstrom, P

Brown, J

Vedapuri, S

Schable, CA

Khan, AS

Lerche, NW

Schweizer, M

Neumann-Haefelin, D

Chapman, LE

Folks, TM

机构：

[1] Ctr Dis Control & Prevent, HIV & Retrovirol Branch, Atlanta, GA 30333 USA

[2] Ctr Dis Control & Prevent, Immunol & Diagnost Branch, Natl Ctr Infect Dis, Atlanta, GA 30333 USA

[3] US FDA, Ctr Biol Evaluat & Res, Lab Retrovirus Res, Bethesda, MD 20892 USA

[4] Univ Calif Lawrence Livermore Natl Lab, Calif Reg Primate Res Ctr, Simian Retrovirus Lab, Livermore, CA 95616 USA

[5] Univ Freiburg, Dept Virol, D-79104 Freiburg, Germany

来源：

NATURE MEDICINE | 1998年 / 4卷 / 04期

关键词：

D O I：

10.1038/nm0498-403

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Studying the transmission of simian retroviruses to humans can help define the importance of these infections to public health. We identified a substantial prevalence (4/231, 1.8%) of infection with simian foamy viruses (SFV) among humans occupationally exposed to nonhuman primates. Evidence of SFV infection included seropositivity, proviral DNA detection and isolation of foamy virus. The infecting SFV originated from an African green monkey (one person) and baboons (three people), These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections.

引用

页码：403 / 407

页数：5

共 32 条

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