An asymmetric synthesis of both enantiomers of the indole alkaloid deplancheine

被引：54

作者：

Allin, SM ^{[1
]}

Thomas, CI

Doyle, K

Elsegood, MRJ

机构：

[1] Loughborough Univ Technol, Dept Chem, Loughborough LE11 3TU, Leics, England

[2] OSI Pharmaceut, Oxford OX4 6LT, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 01期

关键词：

D O I：

10.1021/jo040245k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report a novel, facile and asymmetric approach to both enantiomers of the indole alkaloid deplancheine from a readily available, nonracemic chiral template. The natural product and its antipode are isolated with > 95% ee.

引用

页码：357 / 359

页数：3

共 18 条

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