Genetic relatedness of antibiotic-resistant pneumococci isolated during case clusters

被引：3

作者：

Clarke, SC

Lawrie, D

Diggle, MA

机构：

[1] Stobhill Gen Hosp, Dept Microbiol, Scottish Meningococcus & Pneumococcus Reference L, Glasgow G21 3UW, Lanark, Scotland

[2] Univ Glasgow, Div Infect & Immun, Inst Biomed & Life Sci, Glasgow, Lanark, Scotland

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2004年 / 53卷 / 11期

关键词：

D O I：

10.1099/jmm.0.45733-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Multilocus sequence typing of Streptococcus pneumoniae associated with two case clusters of disease is reported here for the first time. Isolates from the first cluster were serotype 19F, resistant to penicillin and erythromycin, and were characterized as ST 320. Isolates from the second cluster were serogroup 4, resistant to ciprofloxacin, and were characterized as ST 206. Therefore, the isolates from these clusters were antibiotic-resistant, of serotypes infrequently isolated, and of uncommon sequence types.

引用

页码：1097 / 1099

页数：3

共 14 条

[1] The challenge of penicillin-resistant Streptococcus pneumoniae meningitis: Current antibiotic therapy in the 1990s [J].

Bradley, JS ;

Scheld, WM .

CLINICAL INFECTIOUS DISEASES, 1997, 24 :S213-S221

[2] The continued emergence of drug-resistant Streptococcus pneumoniae in the United States: An update from the centers for disease control and prevention's pneumococcal sentinel surveillance system [J].

Butler, JC ;

Hofmann, J ;

Cetron, MS ;

Elliott, JA ;

Facklam, RR ;

Breiman, RF ;

Camp, C ;

Charache, P ;

Dern, R ;

Jackson, M ;

Hadley, WK ;

HoppeBauer, J ;

Jacobs, MR ;

Schreiber, J ;

Boxerbaum, B ;

Menuey, BC ;

Tyler, PG ;

Monahan, J ;

Moore, H ;

Siegel, JD ;

Sherer, D ;

Rogers, P ;

Welch, D ;

Fine, D ;

Radike, J ;

Fiore, A ;

Alexander, M ;

Deaver, K .

JOURNAL OF INFECTIOUS DISEASES, 1996, 174 (05) :986-993

[3] Pneumococcal disease in western Europe: burden of disease, antibiotic resistance and management [J].

Cartwright, K .

EUROPEAN JOURNAL OF PEDIATRICS, 2002, 161 (04) :188-195

[4] A multilocus sequence typing scheme for Streptococcus pneumoniae:: identification of clones associated with serious invasive disease [J].

Enright, MC ;

Spratt, BG .

MICROBIOLOGY-UK, 1998, 144 :3049-3060

[5] Antibiotic resistance in the absence of selective pressure [J].

Gillespie, SH .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2001, 17 (03) :171-176

[6] Treatment of infections due to resistant organisms [J].

Heath, PT ;

Breathnach, AS .

BRITISH MEDICAL BULLETIN, 2002, 61 :231-245

[7] Automated pneumococcal MLST using liquid-handling robotics and a capillary DNA sequencer [J].

Jefferies, J ;

Clarke, SC ;

Diggle, MA ;

Smith, A ;

Dowson, C ;

Mitchell, T .

MOLECULAR BIOTECHNOLOGY, 2003, 24 (03) :303-307

[8] Non-invasive pneumococcal disease and antimicrobial resistance: vaccine implications [J].

Kyaw, MH ;

Clarke, S ;

Jones, IG ;

Campbell, H .

EPIDEMIOLOGY AND INFECTION, 2002, 128 (01) :21-27

[9] Incidence of invasive pneumococcal disease in Scotland, 1988-99 [J].

Kyaw, MH ;

Clarke, S ;

Jones, IG ;

Campbell, H .

EPIDEMIOLOGY AND INFECTION, 2002, 128 (02) :139-147

[10] Serotypes/groups distribution and antimicrobial resistance of invasive pneumococcal isolates: implications for vaccine strategies [J].

Kyaw, MH ;

Clarke, S ;

Edwards, GFS ;

Jones, IG ;

Campbell, H .

EPIDEMIOLOGY AND INFECTION, 2000, 125 (03) :561-572

← 1 2 →