Electrochemical nitric oxide sensors for physiological measurements

被引:154
作者
Privett, Benjamin J. [1 ]
Shin, Jae Ho [2 ]
Schoenfisch, Mark H. [1 ]
机构
[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA
[2] Kwangwoon Univ, Dept Chem, Seoul, South Korea
基金
美国国家卫生研究院;
关键词
NICKEL TETRASULFONATED PHTHALOCYANINE; CARBON-FIBER ELECTRODES; TUMOR-BEARING MICE; COBALT PHTHALOCYANINE; LIQUID-CHROMATOGRAPHY; CHEMICAL BIOLOGY; AQUEOUS-SOLUTION; RELAXING FACTOR; ENDOTHELIUM; MONOXIDE;
D O I
10.1039/b701906h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The important biological roles of nitric oxide (NO) have prompted the development of analytical techniques capable of sensitive and selective detection of NO. Electrochemical sensing, more than any other NO detection method, embodies the parameters necessary for quantifying NO in challenging physiological environments such as blood and the brain. In this tutorial review, we provide a broad overview of the field of electrochemical NO sensors, including design, fabrication, and analytical performance characteristics. Both electrochemical sensors and biological applications are detailed.
引用
收藏
页码:1925 / 1935
页数:11
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