Multiple pathways allow protein secretion across the bacterial outer membrane

被引：225

作者：

Thanassi, DG

Hultgren, SJ

机构：

[1] SUNY Stony Brook, Dept Mol Genet & Microbiol, Stony Brook, NY 11794 USA

[2] SUNY Stony Brook, Ctr Infect Dis, Stony Brook, NY 11794 USA

[3] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(00)00111-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Secretion of proteins across the bacterial outer membrane takes place via a variety of mechanisms from simple one-component systems to complex multicomponent pathways. Secretion pathways can be organized into evolutionarily and functionally related groups, which highlight their relationship with organelle biogenesis. Recent work is beginning to reveal the structure and function of various secretion components and the molecular mechanisms of secretion.

引用

页码：420 / 430

页数：11