Why is cerebral infarction an emergency

被引:3
作者
Bousser, MG [1 ]
机构
[1] Hop Lariboisiere, Serv Neurol, F-75571 Paris 10, France
来源
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2002年 / 186卷 / 07期
关键词
brain infarction; cerebrovascular accident; brain ischemia; thrombolytic therapy;
D O I
10.1016/S0001-4079(19)34217-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The three main criteria for a medical emergency : sudden onset, poor prognosis and possibility of an effective medical treatment apply to cerebral infarction which is the end result of a focal ischemia, occurring all the more rapidly than perfusion pressure is low. Studies devoted to experimental cerebral infarction as well as to thrombolysis in human have shown that the therapeutic window to save the penumbral tissue is very short, presently 3 hours in human for intra venous thrombolysis but with considerable individual variations best assessed by MRI diffusion-perfusion. Caring for the patient who has a cerebral infarction is an emergency because it is necessary, in the very first hours to properly diagnose the infarct and its etiopathogenesis, to detect the vital manifestations to prevent the general complications, to start an antithrombotic treatment, to establish a vital and functional prognosis, to apply in due time the rare surgical or intra-arterial thrombolytic treatments and to start secondary prevention in patients with transient ischemic attacks.
引用
收藏
页码:1159 / 1177
页数:19
相关论文
共 70 条
  • [21] Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset - The ATLANTIS study: A randomized controlled trial
    Clark, WM
    Wissman, S
    Albers, GW
    Jhamandas, JH
    Madden, KP
    Hamilton, S
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (21): : 2019 - 2026
  • [22] Neurological emergencies: acute stroke
    Davenport, R
    Dennis, M
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2000, 68 (03) : 277 - 288
  • [23] The intensive care management of acute ischemic stroke
    Deibert, E
    Diringer, MN
    [J]. NEUROLOGIST, 1999, 5 (06) : 313 - 325
  • [24] *EUR STROK IN, 2000, CEREBROVASC DIS, V10, P335
  • [25] Diagnosis of transient ischemic attack by the nonneurologist - A validation study
    Ferro, JM
    Falcao, I
    Rodrigues, G
    Canhao, P
    Melo, TP
    Oliveira, V
    Pinto, AN
    Crespo, M
    Salgado, AV
    [J]. STROKE, 1996, 27 (12) : 2225 - 2229
  • [26] PREDICTION OF LONG-TERM OUTCOME IN THE EARLY HOURS FOLLOWING ACUTE ISCHEMIC STROKE
    FIORELLI, M
    ALPEROVITCH, A
    ARGENTINO, C
    SACCHETTI, ML
    TONI, D
    SETTE, G
    CAVALLETTI, C
    GORI, MC
    FIESCHI, C
    [J]. ARCHIVES OF NEUROLOGY, 1995, 52 (03) : 250 - 255
  • [27] DIFFUSION AND PERFUSION IMAGING FOR ACUTE STROKE
    FISHER, M
    [J]. SURGICAL NEUROLOGY, 1995, 43 (06): : 606 - 609
  • [28] Timely and appropriate treatment of acute stroke - What's missing from this picture?
    Fontanarosa, PB
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (16): : 1307 - 1309
  • [29] Intra-arterial prourokinase for acute ischemic stroke - The PROACT II study: A randomized controlled trial
    Furlan, A
    Higashida, R
    Wechsler, L
    Gent, M
    Rowley, H
    Kase, C
    Pessin, M
    Ahuja, A
    Callahan, F
    Clark, WM
    Silver, F
    Rivera, F
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (21): : 2003 - 2011
  • [30] Grotta JC, 1999, REV NEUROL, V155, P644