A titanium-catalyzed three-component coupling to generate α,β-unsaturated β-iminoamines

被引：123

作者：

Cao, CS ^{[1
]}

Shi, YH ^{[1
]}

Odom, AL ^{[1
]}

机构：

[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 10期

关键词：

D O I：

10.1021/ja0284714

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The three-component coupling of an amine, alkyne, and isonitrile is facilitated by a titanium complex bearing the N,N-di(pyrrolyl-α-methyl)-N-methylamine (dpma) ligand. From this methodology, α,β-unsaturated β-iminoamines are generated regioselectively with many substrates and are available on multigram scales. Copyright © 2003 American Chemical Society.

引用

页码：2880 / 2881

页数：2

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