Convenient Stille carbonylative cross-couplings using molybdenum hexacarbonyl

被引：35

作者：

Lindh, Jonas ^{[1
]}

Fardost, Ashkan ^{[1
]}

Almeida, Maria

Nilsson, Peter ^{[1
]}

机构：

[1] Uppsala Univ, Uppsala Biomed Ctr, Dept Med Chem, SE-75123 Uppsala, Sweden

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 18期

关键词：

Stille; Molybdenum hexacarbonyl; Diaryl ketones; Palladium; MICROWAVE-PROMOTED AMINOCARBONYLATION; MEDIATED SYNTHESIS; DIARYL KETONES; SOLID-PHASE; ARYL; COMPLEXES; ORGANOSTANNANES; MONOXIDE; C-13; CO;

D O I：

10.1016/j.tetlet.2010.02.165

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium catalysis was used in Stille-type carbonylative cross-couplings employing Mo(CO)(6) as the carbon monoxide source. Robust and convenient transformations were carried out in closed vessels at 100 degrees C, providing a set of diaryl ketones in good yields. Aryl triflates and bromides were used as coupling partners with aryl stannanes. Inclusion of the Mo(CO)(6) destabilizing agent DBU made this protocol operationally simple and suppressed side-product formation. (C) 2010 Elsevier Ltd. All rights reserved.

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页码：2470 / 2472

页数：3

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