DECADE IN REVIEW-IBD IBD-genes, bacteria and new therapeutic strategies

被引：16

作者：

Colombel, Jean-Frederic ^{[1
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Med, New York, NY 10029 USA

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2014年 / 11卷 / 11期

关键词：

INFLAMMATORY-BOWEL-DISEASE; ULCERATIVE-COLITIS; CROHNS-DISEASE; PANETH CELLS;

D O I：

10.1038/nrgastro.2014.170

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

IBD is known to be associated with an abnormal response to an unbalanced gut microbiota in genetically predisposed individuals. The therapeutic goal now is to control progression of the disease. Given the heterogeneity of IBD, the two universes of basic and clinical science must work in parallel to realize the hope of personalized therapy.

引用

页码：652 / 654

页数：3

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