Microwave assisted medicinal chemistry

被引：23

作者：

Alcazar, Jesus

Diels, Gaston

Schoentjes, Bruno

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Cilag, Toledo 45007, Spain

[2] Johnson & JOhnson Pharmaceut Res & Dev, Div Janssen Pharmaceut NV, B-2340 Beerse, Belgium

[3] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Cilag, F-27106 Val De Reuil, France

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 04期

关键词：

microwave; medicinal chemistry; SAR development;

D O I：

10.2174/138955707780363846

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Microwave irradiation has been used to enhance organic reactions since the mid 80's, its use within the field of medicinal chemistry is not so widely evident in the literature. The present review highlights the use of microwave chemistry as an important tool for the fast development of structure activity relationship in several programs related to various therapeutic areas.

引用

页码：345 / 369

页数：25

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