Promising New Sources for Pluripotent Stem Cells

被引：53

作者：

Leeb, Christian ^{[2
]}

Jurga, Marcin ^{[3
]}

McGuckin, Colin ^{[3
]}

Moriggl, Richard ^{[2
]}

Kenner, Lukas ^{[1
,2
]}

机构：

[1] Inst Clin Pathol, Vienna, Austria

[2] Ludwig Boltzmann Inst Canc Res, Vienna, Austria

[3] Cell Therapy Res Inst CTI LYON, F-69800 St Priest, France

来源：

STEM CELL REVIEWS AND REPORTS | 2010年 / 6卷 / 01期

关键词：

Pluripotency; Stem cell; Umbilical cord; Therapy; Induced pluripotent stem cell; UMBILICAL-CORD BLOOD; BONE-MARROW-TRANSPLANTATION; EMBRYONIC-LIKE CELLS; HUMAN SOMATIC-CELLS; EX-VIVO EXPANSION; PERIPHERAL-BLOOD; UNRELATED DONORS; PLACENTAL-BLOOD; HEART-FAILURE; GENERATION;

D O I：

10.1007/s12015-009-9102-0

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Recent findings have placed stem cell research at the forefront of biomedical sciences. Basic research on embryonic stem cells (ESCs) has contributed to our knowledge about the developmental potential and plasticity of stem cells. Furthermore, it has raised hope to use these cells as potential source for regenerative medicine and tissue replacement after injury or disease. Unfortunately, ESCs can also form tumors and they are ethically controversial because they originate from human embryos. This review summarizes findings and therapeutic applications of ESCs and their alternatives: adult stem cells and iPS cells.

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收藏

页码：15 / 26

页数：12

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