Asymmetric hydrogenation of α,β-unsaturated ketones catalyzed by Ru-TPPTS-(S,S)-DPENDS complex in ionic liquids

被引：22

作者：

Wang, Jinbo

Qin, Ruixiang

Fu, Haiyan

Chen, Jun

Feng, Jian

Chen, Hua

Lia, Xianjun

机构：

[1] Sichuan Univ, Coll Chem, Inst Homogeneous Catalysis, Minist Educ,Key Lab Green Chem & Technol, Chengdu 610064, Sichuan, Peoples R China

[2] Weifang Sci & Technol Coll, Coll Chem Engn, Weifang, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2007年 / 18卷 / 07期

关键词：

D O I：

10.1016/j.tetasy.2007.03.021

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric hydrogenation of alpha,beta-unsaturated ketones catalyzed by the achiral ruthenium monophosphine complex RuCl2(TPPTS)(2) [TPPTS: P(m-C6H4SO3Na)(3)] modified by (S,S)-DPENDS [disodium salt of sulfonated (S,S)-1,2-diphenyl-1,2-ethylene-diamine] was investigated in ionic liquid [RMIM]Ts (1-alkyl-3-methytimidazolium p-methylphenylsulfonates, R = ethyl, butyl, octyl, dodecyl). Chemoselectivity of 100% and 75.9% ee were obtained for benzalacetone under the optimized conditions. The resulting products can be easily separated from the catalyst immobilized in ionic liquid [EMIM]Ts by extraction with n-hexane, while the catalyst can be reused seven times without the loss of catalytic activity and enantio selectivity. Especially, the addition of water can improve the performance of the catalyst. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：847 / 851

页数：5

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