Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris

被引：104

作者：

Kikuchi, Yoku

Ito, Kenta ^{[1
]}

Ito, Yoshitaka

Shiroto, Takashi

Tsuburaya, Ryuji

Aizawa, Kentaro

Hao, Kiyotaka

Fukumoto, Yoshihiro

Takahashi, Jun

Takeda, Morihiko

Nakayama, Masaharu

Yasuda, Satoshi

Kuriyama, Shinichi ^{[2
]}

Tsuji, Ichiro ^{[2
]}

Shimokawa, Hiroaki

机构：

[1] Tohoku Univ, Grad Sch Med, Dept Cardiovasc Med, Aoba Ku, Sendai, Miyagi 9808574, Japan

[2] Tohoku Univ, Grad Sch Med, Dept Publ Hlth & Forens Med, Sendai, Miyagi 9808574, Japan

来源：

CIRCULATION JOURNAL | 2010年 / 74卷 / 03期

关键词：

Angina pectoris; Angiogenesis; Myocardial ischemia; Shock wave; RANDOMIZED CONTROLLED-TRIAL; MYOCARDIAL-ISCHEMIA; CELLS; DISEASE; HEART; PIGS;

D O I：

10.1253/circj.CJ-09-1028

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris. Methods and Results: To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects. Conciusions: Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris. (Circ J 2010; 74: 589-591)

引用

页码：589 / 591

页数：3

共 15 条

[11] Extracorporeal shock wave therapy ameliorates hindlimb ischemia in rabbits [J].