Galactoxylomannan does not exhibit cross-reactivity in the Platelia Aspergillus enzyme immunoassay

被引:15
作者
De Jesus, Magdia
Hackett, Emily
Durkin, Michelle
Connolly, Patricia
Casadevall, Arturo
Petraitiene, Ruta
Walsh, Thomas J.
Wheat, L. Joseph
机构
[1] MiraVista Diagnost, Indianapolis, IN 46241 USA
[2] Yeshiva Univ Albert Einstein Coll Med, Bronx, NY 10461 USA
[3] NCI, CRC, Immunocompromised Host Sect, Pediat Oncol Branch, Bethesda, MD 20892 USA
[4] SAIC Frederick Inc, Lab Anim Sci Program, Frederick, MD 21702 USA
关键词
D O I
10.1128/CVI.00368-06
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Given the recent report of a false-positive result in the Platelia Aspergillus enzyme immunoassay in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross-reactions.
引用
收藏
页码:624 / 627
页数:4
相关论文
共 13 条
[1]   Both Th1 and Th2 cytokines affect the ability of monoclonal antibodies to protect mice against Cryptococcus neoformans [J].
Beenhouwer, DO ;
Shapiro, S ;
Feldmesser, M ;
Casadevall, A ;
Scharff, MD .
INFECTION AND IMMUNITY, 2001, 69 (10) :6445-6455
[2]   A yeast under cover:: the capsule of Cryptococcus neoformans [J].
Bose, I ;
Reese, AJ ;
Ory, JJ ;
Janbon, G ;
Doering, TL .
EUKARYOTIC CELL, 2003, 2 (04) :655-663
[3]  
Chaka W, 1997, J IMMUNOL, V159, P2979
[4]   Cryptococcus neoformans galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus galactomannan [J].
Dalle, F ;
Charles, PE ;
Blanc, K ;
Caillot, D ;
Chavanet, P ;
Dromer, F ;
Bonnin, A .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (06) :2929-2931
[5]   GALACTOXYLOMANNANS OF CRYPTOCOCCUS-NEOFORMANS [J].
JAMES, PG ;
CHERNIAK, R .
INFECTION AND IMMUNITY, 1992, 60 (03) :1084-1088
[6]   The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction [J].
McFadden, DC ;
De Jesus, M ;
Casadevall, A .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (04) :1868-1875
[7]   Combination therapy in treatment of experimental pulmonary aspergillosis: Synergistic interaction between an antifungal triazole and an echinocandin [J].
Petraitis, V ;
Petraitiene, R ;
Sarafandi, AA ;
Keleher, AM ;
Lyman, CA ;
Casler, HE ;
Sein, T ;
Groll, AH ;
Becher, J ;
Avila, NA ;
Walsh, TJ .
JOURNAL OF INFECTIOUS DISEASES, 2003, 187 (12) :1834-1843
[8]   RAT MONOCLONAL-ANTIBODIES AGAINST ASPERGILLUS GALACTOMANNAN [J].
STYNEN, D ;
SARFATI, J ;
GORIS, A ;
PREVOST, MC ;
LESOURD, M ;
KAMPHUIS, H ;
DARRAS, V ;
LATGE, JP .
INFECTION AND IMMUNITY, 1992, 60 (06) :2237-2245
[9]   Specificity of a sandwich enzyme-linked immunosorbent assay for detecting Aspergillus galactomannan [J].
Swanink, CMA ;
Meis, JFGM ;
Rijs, AJMM ;
Donnelly, JP ;
Verweij, PE .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (01) :257-260
[10]   FRACTIONATION AND CHARACTERIZATION OF GALACTOXYLOMANNAN FROM CRYPTOCOCCUS-NEOFORMANS [J].
TURNER, SH ;
CHERNIAK, R ;
REISS, E .
CARBOHYDRATE RESEARCH, 1984, 125 (02) :343-349