Microwave-assisted synthesis of 2,5-disubstituted-1,3,4-oxadiazoles

被引:49
作者
Khan, KM [1 ]
Zia-Ullah
Rani, M
Perveen, S
Haider, SM
Choudhary, MI
Atta-ur-Rahman
Voelter, W
机构
[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan
[2] Pakistan Council Sci & Ind Res, Karachi 75280, Pakistan
[3] Univ Tubingen, Inst Physiol Chem, D-72076 Tubingen, Germany
关键词
microwave-irradiation; phosphorous oxychloride; 2,5-disubstituted-1,3,4-oxadiazole;
D O I
10.2174/1570178043488608
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Recent advances in technology have now made microwave energy a more efficient means of heating reactions. Chemical transformations that took hours, or even days, to complete can now be accomplished in minutes. Microwave energy offers numerous benefits for performing synthesis including increased reaction rates, yield enhancements, and cleaner chemistries. 2,5-Disubstituted-1, 3,4-oxadiazoles were synthesized under microwave irradiation and by conventional heating and were structurally characterized by H-1-NMR, EI, IR, UV and elemental analysis.
引用
收藏
页码:50 / 52
页数:3
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