VIEWPOINT Personalized genomic information: preparing for the future of genetic medicine

被引：90

作者：

Guttmacher, Alan E. ^{[1
]}

McGuire, Amy L. ^{[2
]}

Ponder, Bruce ^{[3
]}

Stefansson, Kari ^{[4
]}

机构：

[1] NICHHD, Bethesda, MD 20892 USA

[2] Baylor Coll Med, Ctr Med Eth & Hlth Policy, Houston, TX 77030 USA

[3] Canc Res UK Cambridge Res Inst, Li Ka Shing Ctr, Cambridge CB2 0RE, England

[4] deCODE Genet, IS-101 Reykjavik, Iceland

来源：

NATURE REVIEWS GENETICS | 2010年 / 11卷 / 02期

关键词：

RISK; SUSCEPTIBILITY; VARIANTS; DISEASE; COMMON;

D O I：

10.1038/nrg2735

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The falling cost of sequencing means that we are rapidly approaching an era in which access to personalized genomic information is likely to be widespread. Here, four experts with different insights into the field of genomic medicine answer questions about the prospects for using this type of information. Their responses highlight the diverse range of issues that must be addressed - ranging from scientific to ethical and logistical - to ensure that the potential benefits of personal genomic information outweigh the costs to both individuals and societies.

引用

页码：161 / 165

页数：5

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