Temporal patterns analysis of rat behavior in hole-board

被引:25
作者
Casarrubea, Maurizio [1 ]
Sorbera, Filippina [1 ]
Magnusson, Magnus [2 ]
Crescimanno, Giuseppe [1 ]
机构
[1] Univ Palermo, Dept Expt Med, Human Physiol Sect, I-90133 Palermo, Italy
[2] Univ Iceland, Human Behav Lab, Reykjavik, Iceland
关键词
Hole-board; Anxiety; t-pattern analysis; Exploratory behavior; Head-dip; Edge-sniff; Rat; ELEVATED PLUS-MAZE; NEUROBEHAVIORAL STRESS RESEARCH; GROOMING ANALYSIS ALGORITHM; OPEN-FIELD BEHAVIOR; MULTIVARIATE-ANALYSIS; EXPLORATORY-BEHAVIOR; FEED RESTRICTION; TIME PATTERNS; T-PATTERNS; ANXIETY;
D O I
10.1016/j.bbr.2009.11.013
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The aim of present research was to analyze the temporal structure of rodent's anxiety-related behavior in hole-board apparatus (HB). Fifteen male Wistar rats were tested for 10 min. Video files, collected for each subject, were coded by means of a software coder and event log files generated for each subject. To assess temporal relationships among behavioral events, log files were processed by means of a t-pattern analysis. 14 two-element t-patterns, four t-patterns encompassing 3 events and 2 t-patterns encompassing 4 and 5 events respectively were revealed. It was demonstrated that rat behavior in HB was mainly structured on the basis of the temporal patterning among exploratory events; these ones were the most structured t-patterns detected and appeared mainly during the first 5 min of exploration, while grooming t-patterns were present prevalently after the fifth minute. Specific t-pattern parameters, such as overall occurrences and mean duration of each given t-pattern in each subject, were also studied. Present research: (a) reports for the first time that some behavioral events occur sequentially and with significant constraints on the interval lengths separating them; (b) presents the temporal flows of some behavioral elements through multimodal behavioral vectors; (c) could also be used to improve HB test reliability and its ability to detect even small induced behavioral changes. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:124 / 131
页数:8
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