Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease

被引：61

作者：

Jorm, AF ^{[1
]}

Masaki, KH

Davis, DG

Hardman, J

Nelson, J

Markesbery, WR

Petrovitch, H

Ross, GW

White, LR

机构：

[1] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia

[2] Kuakini Med Ctr, Honolulu Asia Aging Study, Honolulu, HI USA

[3] Univ Hawaii, John A Burns Sch Med, Dept Geriatr Med, Honolulu, HI 96822 USA

[4] Univ Hawaii, John A Burns Sch Med, Dept Internal Med, Honolulu, HI 96822 USA

[5] Honolulu Dept Vet Affairs, Honolulu, HI USA

[6] Univ Kentucky, Dept Pathol & Lab Med, Lexington, KY USA

[7] Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA

来源：

NEUROLOGY | 2004年 / 63卷 / 10期

关键词：

D O I：

10.1212/01.WNL.0000144348.70643.F2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The validity of memory complaints as a predictor of Alzheimer disease ( AD) was assessed in 237 Japanese-American men autopsied at ages 74 to 97 years. These men were free of dementia at the time memory complaints were assessed 1 to 11 years earlier. Memory complaints were found to predict the neuropathologic diagnosis of AD after adjusting for age, time to death, education, depression, and cognitive functioning.

引用

页码：1960 / 1961

页数：2

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