Rapid synthesis of oligosaccharide moieties of globotriaosylceramide using fluorous protective group

被引：51

作者：

Miura, T ^{[1
]}

Inazu, T ^{[1
]}

机构：

[1] Noguchi Inst, Itabashi Ku, Tokyo 1730003, Japan

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 09期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0040-4039(03)00091-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of the Bfp (bisfluorous chain type propanoyl) group as a fluorous protective group made it possible to rapidly synthesize galabiose and the Gb3 oligosaccharide derivatives by a simple fluorous-organic extraction purification. The fluorous oligosaccharide synthesis using the Bfp group is an excellent strategic alternative to solid phase oligosaccharide synthesis, and removes some of the disadvantages of the solid phase method. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：1819 / 1821

页数：3

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