Autoimmune etiology of complex regional pain syndrome (M.!Sudeck)

被引:59
作者
Blaes, F
Schmitz, K
Tschernatsch, M
Kaps, M
Krasenbrink, I
Hempelmann, G
Bräu, ME
机构
[1] Univ Giessen, Dept Neurol, D-35385 Giessen, Germany
[2] Univ Giessen, Dept Anesthesiol, D-35385 Giessen, Germany
关键词
D O I
10.1212/01.WNL.0000143066.58498.BA
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Sera of 12 patients with complex regional pain syndrome ( CRPS) were tested for the occurrence of autoantibodies against nervous system structures. Immunohistochemistry revealed autoantibodies against autonomic nervous system structures in 5 of 12 (41.6%) of the patients. Western blot analysis showed neuronal reactivity in 11 of 12 (91.6%) patients. The authors hypothesize that CRPS can result from an autoimmune process against the sympathetic nervous system.
引用
收藏
页码:1734 / 1736
页数:3
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