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IgCAMs: bidirectional signals underlying neurite growth

被引：85
作者：
Kamiguchi, H
Lemmon, V
机构：
[1] RIKEN, Brain Sci Inst, Dev Brain Sci Grp, Wako, Saitama 3510198, Japan
[2] Case Western Reserve Univ, Dept Neurosci, Cleveland, OH 44106 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 05期
关键词：
D O I：
10.1016/S0955-0674(00)00138-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Understanding how immunoglobulin superfamily cell adhesion molecules (IgCAMs) regulate nervous system development has lagged behind studies on integrins and cadherins. The recent characterization of IgCAM structures combined with cell biological studies on protein-protein interactions and membrane targeting/trafficking demonstrate that IgCAMs interact in exceedingly complex ways to regulate axonal growth and pathfinding.
引用
收藏
页码：598 / 605
页数：8
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