New stable reagents for the nucleophilic trifluoromethylation. Part 2: Trifluoromethylation with silylated hemiaminals of trifluoroacetaldehyde

被引：42

作者：

Billard, T ^{[1
]}

Langlois, BR ^{[1
]}

Blond, G ^{[1
]}

机构：

[1] Univ Lyon 1, Lab Synth Electrosynth & React Composes Organ Flu, UMR 5622, F-69622 Villeurbanne, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 45期

关键词：

trifluoromethylation; fluoral; hemiaminal; trifluoromethylcarbinol;

D O I：

10.1016/S0040-4039(00)01552-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New reagents for the nucleophilic trifluoromethylation have been easily synthesized from fluoral hemiketal. They provide silylated trifluoromethylcarbinol from non-enolizable carbonyl compounds. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8777 / 8780

页数：4

共 6 条

[1] Banks R.E., 1994, ORGANOFLUORINE CHEM
[2] New stable reagents for the nucleophilic trifluoromethylation.: 1.: Trifluoromethylation of carbonyl compounds with N-formylmorpholine derivatives
Billard, T
Bruns, S
Langlois, BR
[J]. ORGANIC LETTERS, 2000, 2 (14) : 2101 - 2103
[3] Filler R., 1993, ORGANOFLUORINE COMPO
[4] HUDLICKY M, 1995, ACS MONOGRAPH, V187
[5] ISHII A, 1999, SYNTHESIS-STUTTGART, P1731
[6] Perfluoroalkylation with organosilicon reagents
Prakash, GKS
Yudin, AK
[J]. CHEMICAL REVIEWS, 1997, 97 (03) : 757 - 786

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