Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo)

被引:55
作者
Ficker, CE
Smith, ML
Susiarti, S
Leaman, DJ
Irawati, Ç
Arnason, JT
机构
[1] Carleton Univ, Dept Biol, Ottawa, ON K1S 5B6, Canada
[2] Indonesian Inst Sci, Herbarium Bogoriense, Bogor 16122, Indonesia
[3] Univ Ottawa, Dept Biol, Ottawa, ON K1N 6N5, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Zingiberaceae; ginger; antifungal resistance; pathogenic fungi; Borneo ethnobotany; traditional phytomedicine;
D O I
10.1016/S0378-8741(03)00009-6
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially Alpinia galanga, Curcuma zedoaria and Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:289 / 293
页数:5
相关论文
共 13 条
[1]   Antifungal resistance trends towards the year 2000 - Implications for therapy and new approaches [J].
Alexander, BD ;
Perfect, JR .
DRUGS, 1997, 54 (05) :657-678
[2]  
Burtt B.L., 1976, Fl. Males. Bull, V29, P2599
[3]   THE MEDICINAL-PLANTS OF GUNUNG-LEUSER-NATIONAL-PARK, INDONESIA [J].
ELLIOTT, S ;
BRIMACOMBE, J .
JOURNAL OF ETHNOPHARMACOLOGY, 1987, 19 (03) :285-317
[4]   Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts [J].
Ficker, CE ;
Arnason, JT ;
Vindas, PS ;
Alvarez, LP ;
Akpagana, K ;
Gbéassor, M ;
De Souza, C ;
Smith, ML .
MYCOSES, 2003, 46 (1-2) :29-37
[5]   MEDICINAL-PLANTS FROM RIAU PROVINCE, SUMATRA, INDONESIA .1. USES [J].
GROSVENOR, PW ;
GOTHARD, PK ;
MCWILLIAM, NC ;
SUPRIONO, A ;
GRAY, DO .
JOURNAL OF ETHNOPHARMACOLOGY, 1995, 45 (02) :75-95
[7]   Antifungal activity of extracts from medicinal plants used by First Nations Peoples of eastern Canada [J].
Jones, NP ;
Arnason, JT ;
Abou-Zaid, M ;
Akpagana, K ;
Sanchez-Vindas, P ;
Smith, ML .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 73 (1-2) :191-198
[8]  
LEAMAN DJ, 1996, THESIS U OTTAWA OTTA
[9]   ANTIBIOTIC SCREENING OF MEDICINAL-PLANTS OF THE BRITISH-COLUMBIAN NATIVE PEOPLES [J].
MCCUTCHEON, AR ;
ELLIS, SM ;
HANCOCK, REW ;
TOWERS, GHN .
JOURNAL OF ETHNOPHARMACOLOGY, 1992, 37 (03) :213-223
[10]   Antimicrobial activity of extracts of eastern North American hardwood trees and relation to traditional medicine [J].
Omar, S ;
Lemonnier, B ;
Jones, N ;
Ficker, C ;
Smith, ML ;
Neema, C ;
Towers, GHN ;
Goel, K ;
Arnason, JT .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 73 (1-2) :161-170