Binol-derived monodentate phosphites and phosphoramidites with phosphorus stereogenic centers: Novel ligands for transition-metal catalysis

被引：99

作者：

Reetz, MT ^{[1
]}

Ma, JA ^{[1
]}

Goddard, R ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 03期

关键词：

asymmetric catalysis; hydrogenation; P ligands; phosphites; rhodium;

D O I：

10.1002/anie.200461624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Buried in the symmetry: Phosphorylation of ortho-substituted binol derivatives leads to monodentate phosphites (X = OR) or phosphoramidites (X = NR2) having stereogenic centers at phosphorus (see scheme). Such compounds are excellent ligands in rhodium-catalyzed olefin-hydrogenation (95-99% ee) surpassing the C2-symmetric parent ligands.

引用

页码：412 / 415

页数：4

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