Immune-mediated clearance of virus from the central nervous system

被引：30

作者：

Binder, GK ^{[1
]}

Griffin, DE ^{[1
]}

机构：

[1] Johns Hopkins Bloomberg Sch Publ Hlth, W Harry Feinstone Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 05期

关键词：

central nervous system; virus replication; immune system;

D O I：

10.1016/S1286-4579(03)00047-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immune-mediated clearance of virus from the central nervous system (CNS) differs from that of the other organs. Mechanisms of virus control are largely dependent upon the target cell type. Although cytolytic T lymphocytes may mediate clearance of virus from glial cells, non-cytolytic mechanisms mediated by antibody and cytokines dominate clearance from neurons. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：439 / 448

页数：10

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