Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing

被引：286

作者：

Giocomo, Lisa M.

Zilli, Eric A.

Fransen, Erik

Hasselmo, Michael E.

机构：

[1] Boston Univ, Dept Psychol, Ctr Memory & Brain, Program Neurosci, Boston, MA 02215 USA

[2] Royal Inst Technol, Sch Comp Sci & Commun, SE-10044 Stockholm, Sweden

[3] Stockholm Brain Inst, SE-10044 Stockholm, Sweden

来源：

SCIENCE | 2007年 / 315卷 / 5819期

关键词：

CORTEX LAYER-II; HEAD DIRECTION CELLS; PATH-INTEGRATION; PLACE CELLS; NEURONS; MODEL; REPRESENTATION; HIPPOCAMPUS; MECHANISMS; DYNAMICS;

D O I：

10.1126/science.1139207

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Grid cells in layer II of rat entorhinal cortex fire to spatial locations in a repeating hexagonal grid, with smaller spacing between grid fields for neurons in more dorsal anatomical locations. Data from in vitro whole-cell patch recordings showed differences in frequency of subthreshold membrane potential oscillations in entorhinal neurons that correspond to different positions along the dorsal-to-ventral axis, supporting a model of physiological mechanisms for grid cell responses.

引用

页码：1719 / 1722

页数：4

共 28 条

[11] Spatial representation in the entorhinal cortex [J].