Enantiopure tetrahydro-β-carbolines via Pictet-Spengler reactions with N-sulfinyl tryptamines

被引：75

作者：

Gremmen, C ^{[1
]}

Willemse, B ^{[1
]}

Wanner, MJ ^{[1
]}

Koomen, GJ ^{[1
]}

机构：

[1] Univ Amsterdam, Inst Mol Chem, NL-1018 WS Amsterdam, Netherlands

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 13期

关键词：

D O I：

10.1021/ol006034t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The influence of N-sulfinyl chiral auxiliaries on the stereochemistry of the Pictet-Spengler reaction has been investigated. From enantiopure (R)-N-beta-toluenesulfinyltryptamine a new and efficient route to enantiopure tetrahydro-beta-carbolines has been established.

引用

页码：1955 / 1958

页数：4

共 27 条

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