A pincer auxiliary to force difficult lactamisations

被引：21

作者：

Bieräugel, H

Schoemaker, HE

Hiemstra, H

van Maarseveen, JH

机构：

[1] Univ Amsterdam, Inst Mol Chem, NL-1018 WS Amsterdam, Netherlands

[2] DSM Res & Patents, Life Sci Prod, NL-6160 MD Geleen, Netherlands

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 11期

关键词：

D O I：

10.1039/b303836j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method to cyclise peptides is reported based on insertion of a salicylaldehyde derived pincer auxiliary in the linear precursor sequence. H-betaAla-Phe-OH and H-PhebetaAla- OH were chosen as representative model peptides.

引用

页码：1830 / 1832

页数：3

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