Stereoselective construction of the key intermediate for the synthesis of the tetrahydropyranyl antifungal agents (+)-restricticin and (+)-lanomycin

被引：6

作者：

Honda, T ^{[1
]}

Satoh, A ^{[1
]}

Yamada, T ^{[1
]}

Hayakawa, T ^{[1
]}

Kanai, K ^{[1
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 142, Japan

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 03期

关键词：

D O I：

10.1039/a707534k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselective construction of the key intermediate for the synthesis of naturally occurring antifungal agents, such as (+)-restricticin and (+)-lanomycin, has been achieved by employing a chelation-controlled aldol reaction of methyl alpha-methyltetronate with (R)-cyclohexylideneglyceraldehyde as a key step.

引用

页码：397 / 405

页数：9

共 15 条

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