Synthesis of HyBeacons and dual-labelled probes containing 2′-fluorescent groups for use in genetic analysis

被引:29
作者
Dobson, N
McDowell, DG
French, DJ
Brown, LJ
Mellor, JM
Brown, T [1 ]
机构
[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England
[2] LGC Ltd, Teddington TW11 0LY, Middx, England
[3] Univ Southampton, Oswel Res Prod Ltd, Southampton SO16 7PX, Hants, England
关键词
D O I
10.1039/b302855k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An FMOC-protected 2A-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.
引用
收藏
页码:1234 / 1235
页数:2
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