Host immune cellular reactions in corneal neovascularization

被引：11

作者：

Abdelfattah, Nizar S. ^{[1
,2
]}

Amgad, Mohamed ^{[3
]}

Zayed, Amira A. ^{[4
]}

机构：

[1] Univ Calif Los Angeles, Doheny Eye Inst, Los Angeles, CA 90033 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USA

[3] Cairo Univ, Fac Med, Cairo 11956, Egypt

[4] Mayo Clin, Dept Surg, Rochester, MN 55904 USA

来源：

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY | 2016年 / 9卷 / 04期

关键词：

corneal neovascularization; macrophage; Th17; cells; dendritic cells; herpes simplex keratitis; keratoplasty; angiogenesis; lymphangiogenesis; contact lenses; HERPES STROMAL KERATITIS; ANTIGEN-PRESENTING CELLS; DRAINING LYMPH-NODES; EPITHELIAL-CELLS; LANGERHANS CELLS; T-CELLS; DENDRITIC CELLS; SIMPLEX-VIRUS; LYMPHENDOTHELIAL CHARACTERISTICS; ENDOTHELIAL-CELLS;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 [眼科学];

摘要：

Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme - and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.

引用

页码：625 / 633

页数：9

共 110 条

[1]

Aarvak T, 1999, J IMMUNOL, V162, P1246

[2]

Clinical correlates of common corneal neovascular diseases: a literature review [J].