Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi

被引:102
作者
Hunter, Jennifer C. [1 ]
Duc Nguyen [1 ]
Aden, Bashir [2 ]
Al Bandar, Zyad [2 ]
Al Dhaheri, Wafa [2 ]
Abu Elkheir, Kheir [2 ]
Khudair, Ahmed [2 ]
Al Mulla, Mariam [2 ]
El Saleh, Feda [2 ]
Imambaccus, Hala [3 ]
Al Kaabi, Nawal [3 ]
Sheikh, Farrukh Amin [3 ]
Sasse, Jurgen [3 ]
Turner, Andrew [3 ]
Wareth, Laila Abdel [3 ]
Weber, Stefan [3 ]
Al Ameri, Asma [4 ]
Abu Amer, Wesal [4 ]
Alami, Negar N. [1 ]
Bunga, Sudhir [1 ]
Haynes, Lia M. [1 ]
Hall, Aron J. [1 ]
Kallen, Alexander J. [1 ]
Kuhar, David [1 ]
Huong Pham [1 ]
Pringle, Kimberly [1 ]
Tong, Suxiang [1 ]
Whitaker, Brett L. [1 ]
Gerber, Susan I. [1 ]
Al Hosani, Farida Ismail [2 ]
机构
[1] Ctr Dis Control & Prevent, Atlanta, GA USA
[2] Hlth Author Abu Dhabi, Abu Dhabi, U Arab Emirates
[3] Abu Dhabi Hlth Serv Co, Abu Dhabi, U Arab Emirates
[4] Sheikh Khalifa Med City, Mol Diagnost Lab, Abu Dhabi, U Arab Emirates
关键词
SAUDI-ARABIA; FAMILY CLUSTER; OUTBREAK; RIYADH; JEDDAH;
D O I
10.3201/eid2204.151615
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013 May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities.
引用
收藏
页码:647 / 656
页数:10
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