Influence of salt on colloidal lithography of albumin

被引:8
作者
Geng, D. L. [1 ]
Miao, Y. H. [1 ]
Helseth, L. E. [1 ]
机构
[1] Nanyang Technol Univ, Div Phys & Appl Phys, Sch Phys & Math Sci, Singapore 639798, Singapore
关键词
D O I
10.1021/la063652v
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We investigate the influence of salt on colloidal lithography of biomolecular patterns. Albumin labeled with fluorescein isothiocyanate (FITC) was adsorbed on polyelectrolyte-coated glass substrates covered by negatively charged colloids using fluorescence microscopy. After removing the colloids, a well-defined albumin pattern remains, and we study how the pattern changes upon adding salt to the protein solution. The proposed method is simple and cheap and can be used to create stable one- and two-dimensional biomolecular arrays.
引用
收藏
页码:8480 / 8484
页数:5
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