Review of Plants and Their Constituents in the Therapy of Cerebral Ischemia

被引:18
作者
Behravan, Effat [1 ]
Razavi, Bibi Marjan [2 ]
Hosseinzadeh, Hossein [3 ]
机构
[1] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynamy & Toxicol, Mashhad, Iran
[2] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynamy & Toxicol, Targeted Drug Delivery Res Ctr, Mashhad, Iran
[3] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynamy & Toxicol, Pharmaceut Res Ctr, Mashhad, Iran
关键词
cerebral ischemia; stroke; plants; herbs; INDUCED NEURONAL DEATH; GINKGO-BILOBA EXTRACT; OXIDATIVE DAMAGE; ARTERY OCCLUSION; GLOBAL-ISCHEMIA; BETA-CAROTENE; BRAIN-INJURY; REPERFUSION INJURY; INFARCT VOLUME; RAT-BRAIN;
D O I
10.1002/ptr.5187
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Cerebral ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This leads to cerebral hypoxia and thus to the death of neuronal cells or stroke. The limited number of medicines currently available for patients following ischemic stroke and insufficient data on efficiency of these chemicals in the treatment of stroke led us to the search for novel therapeutic approaches. Recent studies have focused on the possible capacity of natural compounds extracted from vegetables and fruits, to prevent human disabilities caused by cerebral ischemia. In this review, we will discuss some plants and their constituents that may protect brain ischemia or delay the neurological disorders following a stroke. We have reviewed different studies in scientific databases that investigate herbal compounds and their effects on cerebral ischemia. Copyright (C) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:1265 / 1274
页数:10
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