Synthesis of the first chiral, functionalised-bridged resorcinarenes in asymmetric catalysis: Evidence for intracavity asymmetric catalysis

被引：28

作者：

Arnott, G

Heaney, H

Hunter, R ^{[1
]}

Page, PCB

机构：

[1] Univ Cape Town, Dept Chem, ZA-7701 Rondebosch, South Africa

[2] Loughborough Univ Technol, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 2004卷 / 24期

关键词：

bridged resorcinarenes; chiral resorcinarenes; diethylzinc addition; asymmetric catalysis; intracavity catalysis;

D O I：

10.1002/ejoc.200400615

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methodology is presented for synthesis of the first examples of chiral, bridged resorcinarenes with functionality in the bridge as possible sites for intracavity asymmetric catalysis. A preliminary study comparing unfunctionalised with functionalised lines using the enantio selective addition of diethylzinc to benzaldehyde as a probe reaction, provides compelling evidence for intracavity catalysis. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).

引用

页码：5126 / 5134

页数：9

共 42 条

[1] Synthesis, optical resolution and complexation properties of inherently chiral monoalkylated p-tert-butyl-(1,2)-calix[4]crown ethers [J].