Synthesis of Δ3-pyrrolines and Δ3-tetrahydropyridines via microwave-accelerated ring-closing metathesis

被引:37
作者
Grigg, R [1 ]
Martin, W
Morris, J
Sridharan, V
机构
[1] Univ Leeds, Sch Chem, Divers & Automated Synth MIDAS Ctr, Leeds LS2 9JT, W Yorkshire, England
[2] GlaxoSmithKline, Proc Res & Dev, Stevenage SG1 2NY, Herts, England
关键词
D O I
10.1016/s0040-4039(03)01080-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Microwave irradiation effects ring-closing metathesis of electron-deficient and sterically conjested double bonds with a drastic reduction in reaction time and reduced catalyst loading. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
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页码:4899 / 4901
页数:3
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