Role of B-cell and Fc receptors in the selection of T-cell epitopes

被引：39

作者：

Amigorena, S ^{[1
]}

Bonnerot, C ^{[1
]}

机构：

[1] Inst Curie, INSERM, CJF9501, F-75005 Paris, France

来源：

CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(98)80037-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The role of specific receptors in antigen internalization and presentation to helper T lymphocytes has been known for more than ten years. However, recent work indicates that internalization may not always be sufficient for antigen presentation. Indeed, antigen receptors such as B-cell receptors and Fc receptors may also be involved in the post-endocytic transport events that determine selectively the delivery of antigens to different endocytic compartments and thereby the presentation of different T-cell epitopes.

引用

页码：88 / 92

页数：5

共 42 条

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