DAGchainer: a tool for mining segmental genome duplications and synteny

被引:255
作者
Haas, BJ [1 ]
Delcher, AL [1 ]
Wortman, JR [1 ]
Salzberg, SL [1 ]
机构
[1] Inst Genome Res, Rockville, MD 20850 USA
关键词
D O I
10.1093/bioinformatics/bth397
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Given the positions of protein-coding genes along genomic sequence and probability values for protein alignments between genes, DAGchainer identifies chains of gene pairs sharing conserved order between genomic regions, by identifying paths through a directed acyclic graph (DAG). These chains of collinear gene pairs can represent segmentally duplicated regions and genes within a single genome or syntenic regions between related genomes. Automated mining of the Arabidopsis genome for segmental duplications illustrates the use of DAGchainer.
引用
收藏
页码:3643 / 3646
页数:4
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