Structural role of guest molecules in rapid and sensitive supramolecular assembling system based on β-cyclodextrin-conjugated poly(ε-lysine)

被引：12

作者：

Choi, HS

Takahashi, A

Ooya, T

Yui, N

机构：

[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Tatsunokuchi, Ishikawa 9231292, Japan

[2] Japan Adv Inst Sci & Technol, COE Program Century 21, Tatsunokuchi, Ishikawa 9231292, Japan

来源：

MACROMOLECULES | 2004年 / 37卷 / 26期

关键词：

D O I：

10.1021/ma0487610

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Supramolecular assembling systems governed by intermolecular cooperative host-guest complexation and ionic interactions were investigated based on beta-cyclodextrin-conjugated poly(E-lysine) as a supramolecular host and several hydrophobic guest moieties. The geometric conformations for the inclusion complexation were characterized by 2D-ROESY NMR, and the pH- and thermoreversible properties were investigated by UV-vis measurements. In addition, systematic kinetics and thermodynamics of the supramolecular formation were studied by stopped-flow spectrophotometry and isothermal titration calorimetry, respectively. The trajectories of the binding site, the penetration depth of the guest moiety inside the beta-cyclodextrin, ionic function groups, and other geometrical features gave detailed information on the rapidly stimuli-responsive supramolecular assembly formation.

引用

页码：10036 / 10041

页数：6